STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DA2_1997Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. (487 aa)    
Predicted Functional Partners:
nifJ
Pyruvate:ferredoxin (flavodoxin) oxidoreductase; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
  
 0.923
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
 
   
 0.919
sucD
succinyl-CoA ligase [GDP-forming] subunit alpha-2; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 0.904
DA2_2828
Pyridine nucleotide-disulfide oxidoreductase family protein.
  
 0.876
gabT
4-aminobutyrate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.801
DA2_1340
Zinc-binding dehydrogenase family protein.
   
 0.781
DA2_3161
Tat (twin-arginine translocation) pathway signal sequence domain protein.
    
 0.780
DA2_0824
Aminotransferase class-III family protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.755
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
 0.738
DA2_0906
Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit.
   
 
 0.729
Your Current Organism:
Desulfovibrio sp. A2
NCBI taxonomy Id: 298701
Other names: D. sp. A2
Server load: low (20%) [HD]