STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DA2_2736NAD binding domain of 6-phosphogluconate dehydrogenase family protein. (287 aa)    
Predicted Functional Partners:
nifJ
Pyruvate:ferredoxin (flavodoxin) oxidoreductase; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
  
 
  0.851
pta
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
     
 0.828
acsm4
Acyl-coenzyme A synthetase ACSM4.
  
 
 0.779
hyi
Hydroxypyruvate isomerase; Belongs to the hyi family.
 
 
 0.752
DA2_2180
hpcH/HpaI aldolase/citrate lyase family protein; Belongs to the HpcH/HpaI aldolase family.
 
 
 0.746
DA2_0227
D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein.
 
  
 0.700
acsA
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.693
DA2_3069
Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family.
  
 
 0.693
DA2_3288
acetate--CoA ligase.
  
 
 0.693
DA2_2561
4Fe-4S binding domain protein.
    
 0.674
Your Current Organism:
Desulfovibrio sp. A2
NCBI taxonomy Id: 298701
Other names: D. sp. A2
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.