Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PANX1Pannexin; Structural component of the gap junctions and the hemichannels. (433 aa)    
Predicted Functional Partners:
PANX2
Pannexin-2; Belongs to the pannexin family.
     
 0.931
P2RX6
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.
     
 0.828
CASP7
Caspase-7; Belongs to the peptidase C14A family.
    
 
 0.762
CASP3
Caspase-3; Belongs to the peptidase C14A family.
    
 
 0.756
GRPR
Gastrin-releasing peptide receptor.
    
 
 0.713
P2RX1
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
     
 0.700
GJB1
Gap junction beta-1 protein.
      
 0.695
GJA1
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.676
CALHM1
Calcium homeostasis modulator protein 1.
      
 0.662
SUGT1
Suppressor of G2 allele of SKP1.
     
  0.610
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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