Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PHOX2BPaired mesoderm homeobox protein 2B. (294 aa)    
Predicted Functional Partners:
PHOX2A
Paired mesoderm homeobox protein 2A.
   
 
 0.789
DBH
Dopamine beta-hydroxylase.
   
 
 0.718
HAND2
Heart-and neural crest derivatives-expressed protein 2.
   
 
 0.688
TH
Tyrosine 3-monooxygenase.
   
  
 0.658
LOC110473828
Phenylalanine-4-hydroxylase.
   
  
 0.658
SOX10
Transcription factor SOX-10.
      
 0.636
PRDM12
PR domain zinc finger protein 12; Involved in the positive regulation of histone H3-K9 dimethylation; Belongs to the class V-like SAM-binding methyltransferase superfamily.
      
 0.626
ASCL1
Achaete-scute 1.
   
 
 0.570
GATA3
GATA-binding factor 3.
    
 
 0.569
EDN3
Endothelin-3.
      
 0.568
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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