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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PHOX2BPaired mesoderm homeobox protein 2B. (294 aa)    
Predicted Functional Partners:
HAND2
Heart-and neural crest derivatives-expressed protein 2.
   
 
 0.553
DBH
Dopamine beta-hydroxylase.
   
  
 0.551
GATA3
GATA-binding factor 3.
      
 0.519
SOX10
Transcription factor SOX-10.
      
 0.499
TH
Tyrosine 3-monooxygenase.
   
  
 0.485
ASCL1
Achaete-scute 1.
   
 
 0.476
LOC110473828
Phenylalanine-4-hydroxylase.
   
  
 0.471
EDN3
Endothelin-3.
      
 0.459
INSM2
Insulinoma-associated protein 2.
   
  
 0.402
INSM1
Insulinoma-associated protein 1.
   
  
 0.402
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.