| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CLPX | ENSLSDP00000000815 | ENSLSDP00000015926 | ENSLSDP00000000815 | ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial. | Small ubiquitin-related modifier 3-like. | 0.409 |
| CLPX | SUMO2 | ENSLSDP00000015926 | ENSLSDP00000020453 | ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial. | Small ubiquitin-related modifier. | 0.409 |
| CLPX | UBL3 | ENSLSDP00000015926 | ENSLSDP00000000052 | ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial. | Ubiquitin-like protein. | 0.450 |
| ENSLSDP00000000815 | CLPX | ENSLSDP00000000815 | ENSLSDP00000015926 | Small ubiquitin-related modifier 3-like. | ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial. | 0.409 |
| ENSLSDP00000000815 | NAE1 | ENSLSDP00000000815 | ENSLSDP00000008371 | Small ubiquitin-related modifier 3-like. | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | 0.494 |
| ENSLSDP00000000815 | NEDD8 | ENSLSDP00000000815 | ENSLSDP00000011106 | Small ubiquitin-related modifier 3-like. | Ubiquitin-like protein Nedd8. | 0.866 |
| ENSLSDP00000000815 | SUMO1 | ENSLSDP00000000815 | ENSLSDP00000000032 | Small ubiquitin-related modifier 3-like. | Small ubiquitin-related modifier 1. | 0.974 |
| ENSLSDP00000000815 | SUMO2 | ENSLSDP00000000815 | ENSLSDP00000020453 | Small ubiquitin-related modifier 3-like. | Small ubiquitin-related modifier. | 0.902 |
| ENSLSDP00000000815 | UBA5 | ENSLSDP00000000815 | ENSLSDP00000007852 | Small ubiquitin-related modifier 3-like. | Ubiquitin-like modifier-activating enzyme 5. | 0.444 |
| ENSLSDP00000000815 | UBL3 | ENSLSDP00000000815 | ENSLSDP00000000052 | Small ubiquitin-related modifier 3-like. | Ubiquitin-like protein. | 0.497 |
| ENSLSDP00000000815 | UFM1 | ENSLSDP00000000815 | ENSLSDP00000024449 | Small ubiquitin-related modifier 3-like. | Ubiquitin-fold modifier 1. | 0.496 |
| NAE1 | ENSLSDP00000000815 | ENSLSDP00000008371 | ENSLSDP00000000815 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | Small ubiquitin-related modifier 3-like. | 0.494 |
| NAE1 | NEDD8 | ENSLSDP00000008371 | ENSLSDP00000011106 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | Ubiquitin-like protein Nedd8. | 0.990 |
| NAE1 | SUMO1 | ENSLSDP00000008371 | ENSLSDP00000000032 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | Small ubiquitin-related modifier 1. | 0.520 |
| NAE1 | SUMO2 | ENSLSDP00000008371 | ENSLSDP00000020453 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | Small ubiquitin-related modifier. | 0.494 |
| NAE1 | UBA5 | ENSLSDP00000008371 | ENSLSDP00000007852 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | Ubiquitin-like modifier-activating enzyme 5. | 0.475 |
| NAE1 | UBL3 | ENSLSDP00000008371 | ENSLSDP00000000052 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | Ubiquitin-like protein. | 0.408 |
| NAE1 | UFM1 | ENSLSDP00000008371 | ENSLSDP00000024449 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | Ubiquitin-fold modifier 1. | 0.630 |
| NEDD8 | ENSLSDP00000000815 | ENSLSDP00000011106 | ENSLSDP00000000815 | Ubiquitin-like protein Nedd8. | Small ubiquitin-related modifier 3-like. | 0.866 |
| NEDD8 | NAE1 | ENSLSDP00000011106 | ENSLSDP00000008371 | Ubiquitin-like protein Nedd8. | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | 0.990 |