STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CASP8Caspase-8; Belongs to the peptidase C14A family. (501 aa)    
Predicted Functional Partners:
FADD
FAS-associated death domain protein.
   
0.992
RIPK1
Receptor-interacting serine/threonine-protein kinase 1.
   
 0.985
TRADD
Tumor necrosis factor receptor type 1-associated DEATH domain protein.
    
 0.984
CFLAR
CASP8 and FADD-like apoptosis regulator; Belongs to the peptidase C14A family.
   
0.981
CASP3
Caspase-3; Belongs to the peptidase C14A family.
  
0.972
BID
BH3-interacting domain death agonist; Counters the protective effect of Bcl-2.
   
 0.964
CASP6
Caspase-6; Belongs to the peptidase C14A family.
   
0.951
LOC110469493
Mucosa-associated lymphoid tissue lymphoma translocation protein 1.
   
 0.950
MALT1
Mucosa-associated lymphoid tissue lymphoma translocation protein 1.
   
 0.950
CASP7
Caspase-7; Belongs to the peptidase C14A family.
   
0.946
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.