STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ESRRGEstrogen-related receptor gamma. (458 aa)    
Predicted Functional Partners:
PPARGC1A
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha.
   
 0.866
PPARGC1B
Peroxisome proliferator-activated receptor gamma coactivator 1-beta.
    
 0.810
NRIP1
Nuclear receptor-interacting protein 1.
    
 0.789
LOC110472349
Homeobox protein NANOG.
    
 
 0.743
LOC110472216
POU domain protein.
    
 0.729
NR0B2_1
Nuclear receptor subfamily 0 group B member 2.
    
 0.688
NR0B1
Nuclear receptor subfamily 0 group B member 1.
    
 0.688
NR0B2
Nuclear receptor subfamily 0 group B member 2.
    
 0.664
PRDM15
PR domain zinc finger protein 15.
    
 0.578
MED1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
  0.554
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.