Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1483 aa)    
Predicted Functional Partners:
ROCK1
Rho-associated protein kinase 1.
  
0.999
RHOA
Transforming protein RhoA.
    
 0.980
ENSLSDP00000018611
Protein phosphatase 1 regulatory subunit 12B-like.
   
 0.953
PPP1R12B
Protein phosphatase 1 regulatory subunit.
   
 0.953
PPP1R12A
Protein phosphatase 1 regulatory subunit.
   
 0.953
LIMK2
LIM domain kinase 2.
    
0.949
LIMK1
LIM domain kinase 1.
    
0.949
MYL9
Myosin regulatory light polypeptide 9.
    
 0.943
LOC110467854
Myosin regulatory light chain 2, smooth muscle minor isoform.
    
 0.943
LOC110467855
Myosin regulatory light chain 2, smooth muscle minor isoform.
    
 0.943
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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