Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AP1S2AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (173 aa)    
Predicted Functional Partners:
AP1G1
AP-1 complex subunit gamma.
    
 0.989
AP1M2
AP-1 complex subunit mu-2.
    
 0.981
AP1M1
AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.
    
 0.981
AP1B1
AP complex subunit beta.
    
 0.977
AP1S3
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
  
  
 
0.901
AP4E1
AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family.
   
 0.861
AP2B1
AP complex subunit beta.
    
 0.856
AP4B1
AP complex subunit beta; Belongs to the adaptor complexes large subunit family.
   
 0.841
SYNRG
Synergin gamma.
    
 0.794
AFTPH
Aftiphilin.
    
 0.774
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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