Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ME3Malic enzyme. (542 aa)    
Predicted Functional Partners:
PC
Uncharacterized protein.
   
 0.981
LDHB
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 
 0.976
LOC110468074
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 
 0.974
FH
Fumarate hydratase, mitochondrial.
  
 
 0.972
MDH2
Malate dehydrogenase.
  
 0.964
PDHB
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 
 0.958
PKM
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.958
MDH1
Malate dehydrogenase.
  
 
 0.957
PDHA1
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
   
 0.954
CS
Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.936
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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