Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EFR3AProtein EFR3 A. (823 aa)    
Predicted Functional Partners:
PI4KA
Phosphatidylinositol 4-kinase alpha; Belongs to the PI3/PI4-kinase family.
   
 
 0.927
SEMA3E
Semaphorin-3E; Belongs to the semaphorin family.
      
 0.874
DOK4
Docking protein 4.
      
 0.874
TTC7A
Tetratricopeptide repeat protein 7A.
   
 
 0.859
TTC7B
Tetratricopeptide repeat protein 7B.
   
 
 0.859
ARHGEF2
Rho guanine nucleotide exchange factor 2.
    
   0.719
TMEM150A
Transmembrane protein 150A.
      
 0.644
SEMA3G
Semaphorin-3G; Belongs to the semaphorin family.
      
 0.596
RHEX
Uncharacterized protein.
      
 0.586
KATNAL2
Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.
   
  
 0.581
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
Server load: low (28%) [HD]