Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KLHL18Kelch-like protein 18. (579 aa)    
Predicted Functional Partners:
CUL3
Cullin-3; Belongs to the cullin family.
    
 0.984
RBX1
E3 ubiquitin-protein ligase RBX1.
    
 0.963
NFE2L2
Nuclear factor erythroid 2-related factor 2.
    
 0.915
SQSTM1
Sequestosome-1.
    
 0.878
ENSLSDP00000000870
annotation not available
    
 0.784
UBE2M
NEDD8-conjugating enzyme Ubc12.
    
 0.784
PTMA
Prothymosin alpha.
    
 
 0.746
MCM3
DNA helicase; Belongs to the MCM family.
    
 
 0.718
PALB2
Partner and localizer of BRCA2.
   
 0.710
NUDCD3
NudC domain-containing protein 3.
   
 
 0.701
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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