Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
UNC119BProtein unc-119 B. (239 aa)    
Predicted Functional Partners:
NPHP3
Nephrocystin-3.
    
 0.944
RP2
Protein XRP2; Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.
     
 0.916
ARL3
ADP-ribosylation factor-like protein 3; Belongs to the small GTPase superfamily. Arf family.
    
 0.800
ARL2
ADP-ribosylation factor-like protein 2.
    
 
 0.679
PDE6D
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide [...]
  
   
 0.657
TBCC
Tubulin-specific chaperone C.
     
 0.576
PPIE
Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.
      
 0.559
LOC110470825
ADP-ribosylation factor-like protein 3; Belongs to the small GTPase superfamily. Arf family.
    
 0.549
LZTS1
Leucine zipper putative tumor suppressor 1.
    
   0.513
KLC4
Kinesin light chain 4.
    
 0.509
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
Server load: low (24%) [HD]