Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACE2Angiotensin-converting enzyme. (935 aa)    
Predicted Functional Partners:
AGT
Angiotensinogen; Belongs to the serpin family.
    
 0.977
TMPRSS2
Transmembrane protease serine 2; Belongs to the peptidase S1 family.
    
 
 0.893
REN
Renin; Belongs to the peptidase A1 family.
      
 0.874
AGTR1
Type-1 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.869
SLC6A20
Sodium-and chloride-dependent transporter XTRP3.
   
 
 0.862
DPP4
Dipeptidyl peptidase 4; Belongs to the peptidase S9B family.
      
 0.815
SLC6A19
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
   
 
 0.787
SLC6A18
Solute carrier family 6 (neurotransmitter transporter, amino acid/orphan) member 15/16/17/18/20.
   
 
 0.786
SNX27
Sorting nexin-27.
    
 
 0.745
FURIN
Furin; Belongs to the peptidase S8 family.
      
 0.725
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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