Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SETD2Histone-lysine N-methyltransferase SETD2. (2502 aa)    
Predicted Functional Partners:
IWS1
Protein IWS1.
   
 
 0.933
SUPT5H
Transcription elongation factor SPT5.
   
 
 0.931
SUPT6H
Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family.
  
 
 0.927
POLR2C
DNA-directed RNA polymerase II subunit RPB3.
    
 0.918
CAMKMT
Calmodulin-lysine N-methyltransferase.
     
 0.907
EP400
E1A-binding protein p400.
   
 0.907
CTR9
RNA polymerase-associated protein CTR9.
   
 0.900
SETD1B
Histone-lysine N-methyltransferase SETD1B.
   
 
 0.899
CDC73
Parafibromin.
    
 
 0.899
RTF1
RNA polymerase-associated protein RTF1.
    
 
 0.895
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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