Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HECTD1E3 ubiquitin-protein ligase HECTD1. (2585 aa)    
Predicted Functional Partners:
BIRC6
Baculoviral IAP repeat-containing protein 6.
   
 
 0.905
ZRANB1
Ubiquitin thioesterase ZRANB1.
   
 
 0.864
ZNF622
Zinc finger protein 622.
    
 
 0.856
COPA
Coatomer subunit alpha.
   
   0.843
SMC2
Structural maintenance of chromosomes protein 2.
   
   0.837
SMC4
Structural maintenance of chromosomes protein.
   
   0.786
TRIP12
E3 ubiquitin-protein ligase TRIP12.
   
   0.737
UBR3
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
  
 0.690
MORF4L1
Mortality factor 4-like protein 1.
   
 
 0.663
ARID4B
AT-rich interactive domain-containing protein 4B.
   
   0.652
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.