NR4A1 protein (Lonchura striata) - STRING interaction network

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Score

NR4A1

Nuclear receptor subfamily 4 group A member 1. (587 aa)

Predicted Functional Partners:

BCL2

0.883

FOSB

0.816

EP300

0.775

DUSP6

0.754

FOS

0.742

SIK1

0.689

NCOR2

0.684

NCOR1

0.684

EGR1

0.669

MIDN

0.660

Your Current Organism:

Lonchura striata

NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL2	FOS	ENSLSDP00000018363	ENSLSDP00000003630	Apoptosis regulator Bcl-2.	Proto-oncogene c-Fos.	0.546
BCL2	NR4A1	ENSLSDP00000018363	ENSLSDP00000001180	Apoptosis regulator Bcl-2.	Nuclear receptor subfamily 4 group A member 1.	0.883
DUSP6	EGR1	ENSLSDP00000023711	ENSLSDP00000024752	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.	0.689
DUSP6	NR4A1	ENSLSDP00000023711	ENSLSDP00000001180	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Nuclear receptor subfamily 4 group A member 1.	0.754
DUSP6	SIK1	ENSLSDP00000023711	ENSLSDP00000011332	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Serine/threonine-protein kinase SIK2.	0.767
EGR1	DUSP6	ENSLSDP00000024752	ENSLSDP00000023711	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.689
EGR1	EP300	ENSLSDP00000024752	ENSLSDP00000003382	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.	Histone acetyltransferase p300.	0.669
EGR1	FOS	ENSLSDP00000024752	ENSLSDP00000003630	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.	Proto-oncogene c-Fos.	0.891
EGR1	FOSB	ENSLSDP00000024752	ENSLSDP00000007466	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.	Protein fosB.	0.743
EGR1	NR4A1	ENSLSDP00000024752	ENSLSDP00000001180	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.	Nuclear receptor subfamily 4 group A member 1.	0.669
EGR1	SIK1	ENSLSDP00000024752	ENSLSDP00000011332	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.	Serine/threonine-protein kinase SIK2.	0.654
EP300	EGR1	ENSLSDP00000003382	ENSLSDP00000024752	Histone acetyltransferase p300.	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.	0.669
EP300	FOS	ENSLSDP00000003382	ENSLSDP00000003630	Histone acetyltransferase p300.	Proto-oncogene c-Fos.	0.937
EP300	NCOR1	ENSLSDP00000003382	ENSLSDP00000012950	Histone acetyltransferase p300.	Nuclear receptor corepressor 1.	0.700
EP300	NCOR2	ENSLSDP00000003382	ENSLSDP00000007519	Histone acetyltransferase p300.	Nuclear receptor corepressor 2.	0.700
EP300	NR4A1	ENSLSDP00000003382	ENSLSDP00000001180	Histone acetyltransferase p300.	Nuclear receptor subfamily 4 group A member 1.	0.775
FOS	BCL2	ENSLSDP00000003630	ENSLSDP00000018363	Proto-oncogene c-Fos.	Apoptosis regulator Bcl-2.	0.546
FOS	EGR1	ENSLSDP00000003630	ENSLSDP00000024752	Proto-oncogene c-Fos.	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.	0.891
FOS	EP300	ENSLSDP00000003630	ENSLSDP00000003382	Proto-oncogene c-Fos.	Histone acetyltransferase p300.	0.937
FOS	FOSB	ENSLSDP00000003630	ENSLSDP00000007466	Proto-oncogene c-Fos.	Protein fosB.	0.964