STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PCSK2Neuroendocrine convertase 2; Belongs to the peptidase S8 family. (581 aa)    
Predicted Functional Partners:
SCG5
Neuroendocrine protein 7B2.
   
 
 0.836
CPE
Carboxypeptidase E.
   
  
 0.668
ENSLSDP00000025585
annotation not available
      
 0.610
PTPRN2
Receptor-type tyrosine-protein phosphatase N2.
   
  
 0.595
PTPRN
Protein tyrosine phosphatase receptor type N.
   
  
 0.595
INS
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
 
 0.570
USP24
Ubiquitin carboxyl-terminal hydrolase 24; Belongs to the peptidase C19 family.
      
 0.569
KCNJ11
ATP-sensitive inward rectifier potassium channel 11.
   
  
 0.455
RXFP1
Relaxin receptor 1.
   
 0.450
LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4.
   
 0.450
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.