Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GNAO1Guanine nucleotide-binding protein G(O) subunit alpha. (354 aa)    
Predicted Functional Partners:
ADCY5
Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
   
 0.966
DVL1
Segment polarity protein dishevelled DVL-1.
    
 0.939
MCHR1
Melanin-concentrating hormone receptor 1.
    
  0.934
FZD4
Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.930
PLCB4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
   
 0.930
LOC110475975
Histamine H3 receptor; Belongs to the G-protein coupled receptor 1 family.
    
  0.930
LOC110477964
Endothelin B receptor; Belongs to the G-protein coupled receptor 1 family.
    
 0.929
LOC110470681
Guanine nucleotide-binding protein G(Q) subunit alpha.
  
 
0.929
EDNRB
Endothelin B receptor; Belongs to the G-protein coupled receptor 1 family.
    
  0.928
AGTR2
Type-2 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family.
    
  0.926
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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