HEATR5A protein (Lonchura striata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

HEATR5A

HEAT repeat-containing protein 5A. (2046 aa)

Predicted Functional Partners:

AFTPH

0.853

AP1G1

0.818

AP4E1

0.654

IQCB1

0.652

AP1M2

0.618

AP1M1

0.618

WDR75

0.582

SCFD1

0.580

LOC110476621

0.567

OVCA2

0.567

Your Current Organism:

Lonchura striata

NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFTPH	AP1G1	ENSLSDP00000023535	ENSLSDP00000018972	Aftiphilin.	AP-1 complex subunit gamma.	0.565
AFTPH	AP1M1	ENSLSDP00000023535	ENSLSDP00000011633	Aftiphilin.	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	0.757
AFTPH	AP1M2	ENSLSDP00000023535	ENSLSDP00000011276	Aftiphilin.	AP-1 complex subunit mu-2.	0.757
AFTPH	AP4E1	ENSLSDP00000023535	ENSLSDP00000022924	Aftiphilin.	AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family.	0.540
AFTPH	HEATR5A	ENSLSDP00000023535	ENSLSDP00000001250	Aftiphilin.	HEAT repeat-containing protein 5A.	0.853
AP1G1	AFTPH	ENSLSDP00000018972	ENSLSDP00000023535	AP-1 complex subunit gamma.	Aftiphilin.	0.565
AP1G1	AP1M1	ENSLSDP00000018972	ENSLSDP00000011633	AP-1 complex subunit gamma.	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	0.993
AP1G1	AP1M2	ENSLSDP00000018972	ENSLSDP00000011276	AP-1 complex subunit gamma.	AP-1 complex subunit mu-2.	0.993
AP1G1	AP4E1	ENSLSDP00000018972	ENSLSDP00000022924	AP-1 complex subunit gamma.	AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family.	0.541
AP1G1	HEATR5A	ENSLSDP00000018972	ENSLSDP00000001250	AP-1 complex subunit gamma.	HEAT repeat-containing protein 5A.	0.818
AP1M1	AFTPH	ENSLSDP00000011633	ENSLSDP00000023535	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	Aftiphilin.	0.757
AP1M1	AP1G1	ENSLSDP00000011633	ENSLSDP00000018972	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-1 complex subunit gamma.	0.993
AP1M1	AP1M2	ENSLSDP00000011633	ENSLSDP00000011276	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-1 complex subunit mu-2.	0.901
AP1M1	AP4E1	ENSLSDP00000011633	ENSLSDP00000022924	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family.	0.953
AP1M1	HEATR5A	ENSLSDP00000011633	ENSLSDP00000001250	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	HEAT repeat-containing protein 5A.	0.618
AP1M2	AFTPH	ENSLSDP00000011276	ENSLSDP00000023535	AP-1 complex subunit mu-2.	Aftiphilin.	0.757
AP1M2	AP1G1	ENSLSDP00000011276	ENSLSDP00000018972	AP-1 complex subunit mu-2.	AP-1 complex subunit gamma.	0.993
AP1M2	AP1M1	ENSLSDP00000011276	ENSLSDP00000011633	AP-1 complex subunit mu-2.	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	0.901
AP1M2	AP4E1	ENSLSDP00000011276	ENSLSDP00000022924	AP-1 complex subunit mu-2.	AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family.	0.953
AP1M2	HEATR5A	ENSLSDP00000011276	ENSLSDP00000001250	AP-1 complex subunit mu-2.	HEAT repeat-containing protein 5A.	0.618