STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RECQL4_0ATP-dependent DNA helicase Q4. (913 aa)    
Predicted Functional Partners:
EXO1
Exonuclease 1.
  
 0.966
DNA2
DNA replication ATP-dependent helicase/nuclease DNA2.
   
 0.943
TOP3A
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
  
 0.936
CHTF18
Chromosome transmission fidelity protein 18.
   
 
 0.933
FANCM
Fanconi anemia group M protein.
   
 0.933
LOC110477051
Fanconi anemia group M protein.
   
 0.933
MCM10
Minichromosome maintenance protein 10.
   
 
 0.915
TOPBP1
DNA topoisomerase 2-binding protein 1.
   
 0.914
ATAD5
ATPase family AAA domain-containing protein 5.
   
 0.911
RAD50
DNA repair protein RAD50.
  
 0.901
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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