Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HSF4Heat shock factor protein 4. (509 aa)    
Predicted Functional Partners:
HSBP1
Heat shock factor-binding protein 1.
    
 0.700
HSPA4
Heat shock protein 4.
   
 0.677
HSPA8
Heat shock cognate protein.
    
 0.676
HSPA2
Heat shock protein; Belongs to the heat shock protein 70 family.
    
 0.676
PTGES3
Prostaglandin E synthase 3.
    
 0.675
HSPBP1
Hsp70-binding protein 1.
   
 
 0.668
GSK3B
Glycogen synthase kinase-3 beta; Belongs to the protein kinase superfamily.
    
 0.647
YWHAE
14-3-3 protein epsilon; Belongs to the 14-3-3 family.
    
 0.631
LOC110476439
Heat shock protein HSP 90-alpha.
    
 0.623
LOC110481174
Heat shock protein HSP 90-alpha.
    
 0.623
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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