Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GSDMENon-syndromic hearing impairment protein 5. (501 aa)    
Predicted Functional Partners:
CASP3
Caspase-3; Belongs to the peptidase C14A family.
    
 0.982
CASP7
Caspase-7; Belongs to the peptidase C14A family.
    
 0.969
CENPU
Centromere protein U.
    
 0.660
LOC110474649
Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
     
 0.618
ENSLSDP00000015299
annotation not available
     
 0.618
HMGB2
High mobility group protein B2.
     
 0.601
HMGB1
High mobility group protein B1.
     
 0.601
CASP6
Caspase-6; Belongs to the peptidase C14A family.
    
 0.584
HMGB3
High mobility group protein B3.
     
 0.562
CASP8
Caspase-8; Belongs to the peptidase C14A family.
    
 0.517
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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