Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SIRT4NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily. (315 aa)    
Predicted Functional Partners:
GLUD1
Glutamate dehydrogenase 1, mitochondrial; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
 0.974
SIRT2
NAD-dependent protein deacetylase sirtuin-2.
  
 
0.971
SIRT3
NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.
  
 
0.961
SIRT6
NAD-dependent protein deacetylase sirtuin-6.
  
  
0.961
SIRT7
NAD+-dependent protein deacetylase sirtuin 7.
  
  
0.958
SIRT1
NAD-dependent protein deacetylase sirtuin-1.
  
 
0.956
NAMPT
Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family.
     
 0.941
DLAT
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
    
 0.930
NADSYN1
Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.
    
 0.926
NADK
NAD kinase.
  
 
 0.915
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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