STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HECW2E3 ubiquitin-protein ligase HECW2. (1564 aa)    
Predicted Functional Partners:
PSMD4
26S proteasome non-ATPase regulatory subunit 4.
    
 0.701
RPS27A
Ubiquitin-40S ribosomal protein S27a.
    
 0.690
FUS1
Ubiquitin-60S ribosomal protein L40.
    
 0.690
UBA52
Ubiquitin-60S ribosomal protein L40.
    
 0.684
LOC110471805
Ubiquitin.
    
 0.664
DVL3
Segment polarity protein dishevelled DVL-3.
    
 0.636
DVL1
Segment polarity protein dishevelled DVL-1.
    
 0.636
SMAD4_0
Mothers against decapentaplegic homolog.
   
 0.595
SNAPIN
Mothers against decapentaplegic homolog 4-like.
   
 0.595
ITSN2
Intersectin-2.
    
  0.594
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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