STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HECW2E3 ubiquitin-protein ligase HECW2. (1564 aa)    
Predicted Functional Partners:
ARRDC1
Arrestin domain-containing protein 1.
    
 
 0.676
RPS27A
Ubiquitin-40S ribosomal protein S27a.
    
  0.654
FUS1
Ubiquitin-60S ribosomal protein L40.
    
  0.654
DVL3
Segment polarity protein dishevelled DVL-3.
    
 0.639
DVL1
Segment polarity protein dishevelled DVL-1.
    
 0.639
GJA1
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
    
 0.615
PSMA2
Proteasome subunit alpha type.
    
 0.599
UBE2K
Ubiquitin-conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.579
SMURF1
E3 ubiquitin-protein ligase.
    
 0.578
WBP2
WW domain-binding protein 2.
    
 
 0.576
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.