Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1221 aa)    
Predicted Functional Partners:
GNAS
Guanine nucleotide-binding protein G(S) subunit alpha.
   
 0.965
PRKACB
cAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily.
    
 0.936
RAPGEF4
Rap guanine nucleotide exchange factor 4.
   
 
 0.924
ENPP1
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1.
     
 0.910
ENPP3
Ectonucleotide pyrophosphatase/phosphodiesterase family member 3.
     
 0.910
NTPCR
Cancer-related nucleoside-triphosphatase.
     
 0.906
RAPGEF3-2
Rap guanine nucleotide exchange factor 3.
     
  0.900
NUDT2
Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical].
     
  0.900
ENTPD2
Ectonucleoside triphosphate diphosphohydrolase 2; Belongs to the GDA1/CD39 NTPase family.
   
 
  0.900
GNG7
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
 0.866
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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