STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SNX8Sorting nexin-8. (445 aa)    
Predicted Functional Partners:
GAK
Cyclin-G-associated kinase.
    
 0.945
MSH3
DNA mismatch repair protein Msh3.
   
   0.905
VPS35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 
 0.763
SNX6
Sorting nexin; Involved in several stages of intracellular trafficking.
   
 0.737
SNX5
Sorting nexin; Involved in several stages of intracellular trafficking.
   
 0.737
VPS29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
   
 
 0.705
IGF2R
Cation-independent mannose-6-phosphate receptor.
    
 0.637
DNAJC6
Putative tyrosine-protein phosphatase auxilin.
    
 0.633
VPS26B
Vacuolar protein sorting-associated protein 26B.
    
 
 0.628
VPS26A
Vacuolar protein sorting-associated protein 26A.
    
 
 0.628
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.