Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADAM17Disintegrin and metalloproteinase domain-containing protein 17. (822 aa)    
Predicted Functional Partners:
NOTCH1
Neurogenic locus notch 1.
    
 0.979
NOTCH2
Neurogenic locus notch 2.
    
 0.935
MERTK
Tyrosine-protein kinase Mer.
    
 0.930
ADAM10
Disintegrin and metalloproteinase domain-containing protein 10.
     
0.921
ADAM9
Disintegrin and metalloproteinase domain-containing protein 9.
     
0.910
TIMP3
Metalloproteinase inhibitor 3.
    
 
 0.894
TGFA
Protransforming growth factor alpha.
   
 
 0.880
ARG2
Arginase.
      
 0.874
RHBDF1
Inactive rhomboid protein 1.
    
 0.851
RHBDF2
Inactive rhomboid protein 2.
    
 0.851
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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