STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADAM17Disintegrin and metalloproteinase domain-containing protein 17. (822 aa)    
Predicted Functional Partners:
NOTCH1
Neurogenic locus notch 1.
    
 0.951
TIMP3
Metalloproteinase inhibitor 3.
    
 0.936
NOTCH2
Neurogenic locus notch 2.
    
 0.909
TIMP2
Metalloproteinase inhibitor 2.
    
 0.700
ARL11
ADP-ribosylation factor-like protein 11; Belongs to the small GTPase superfamily. Arf family.
      
 0.605
TGFA
Protransforming growth factor alpha.
   
 
 0.573
SUMO1
Small ubiquitin-related modifier 1.
      
 0.565
NCSTN
Nicastrin.
    
 
 0.561
RHBDF1
Inactive rhomboid protein 1.
    
 0.558
RHBDF2
Inactive rhomboid protein 2.
    
 0.558
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.