Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AMD1S-adenosylmethionine decarboxylase proenzyme. (341 aa)    
Predicted Functional Partners:
SMS
Spermine synthase.
  
 
 0.994
SRM
Spermidine synthase; Belongs to the spermidine/spermine synthase family.
  
 
 0.993
MAT2A
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
   
 
 0.949
MAT1A
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
   
 
 0.949
GNMT
Glycine N-methyltransferase.
     
 0.943
MAT2B
Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.
     
 0.919
DNMT1
DNA methyltransferase 1.
     
 0.903
DNMT3B
DNA (Cytosine-5)-methyltransferase 3B.
     
  0.900
SMOX
Spermine oxidase.
      
 0.873
ODC1
Ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
 
 
 
 0.805
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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