STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SOCS1Suppressor of cytokine signaling 1. (207 aa)    
Predicted Functional Partners:
ELOB
Transcription elongation factor B polypeptide 2.
    
 0.961
ELOC
Transcription elongation factor B polypeptide 1; Belongs to the SKP1 family.
    
 0.957
SOCS3
Suppressor of cytokine signaling 3.
   
 
0.948
INSR
Tyrosine-protein kinase receptor.
    
 0.925
IFNAR1
Interferon alpha/beta receptor 1.
    
 0.853
CUL5
Cullin-5; Belongs to the cullin family.
   
 0.836
JAK3
Tyrosine-protein kinase.
   
 0.821
JAK2
Tyrosine-protein kinase.
   
 0.821
IFNG
Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
   
 
 0.789
STAT3
Signal transducer and activator of transcription.
   
 0.715
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.