Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SMPD3Sphingomyelin phosphodiesterase 3. (660 aa)    
Predicted Functional Partners:
SMPD2
Sphingomyelin phosphodiesterase 2.
     
 0.986
SMPD1
Sphingomyelin phosphodiesterase.
     
 0.967
SMPD4-2
Sphingomyelin phosphodiesterase 4.
     
 0.958
PLPP1
Phospholipid phosphatase 1 isoform X1.
     
 0.948
LOC110483217
Sphingolipid delta(4)-desaturase DES1.
     
 0.941
UGCG
Ceramide glucosyltransferase.
     
 0.940
SGMS1
Phosphatidylcholine:ceramide cholinephosphotransferase 1.
     
 0.934
SGMS2
Phosphatidylcholine:ceramide cholinephosphotransferase 2.
     
 0.934
ASAH1
Acid ceramidase; Belongs to the acid ceramidase family.
     
 0.930
CERK
Ceramide kinase.
     
 0.928
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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