Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FOXP2Forkhead box protein P2. (595 aa)    
Predicted Functional Partners:
ENSLSDP00000001578
annotation not available
 
      0.879
FOXP4
Forkhead box protein P4.
    
 
 0.613
CNTNAP2
Contactin-associated protein-like 2.
      
 0.571
LOC110477747
Contactin-associated protein-like 2.
      
 0.571
TBR1
T-box brain protein 1.
    
 
 0.565
CUX1
Homeobox protein cut-like.
    
 
 0.538
SOX5
Transcription factor SOX-5.
    
 
 0.535
MAMLD1
Mastermind-like domain-containing protein 1.
      
 0.523
MED8
Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
      
 0.520
NUMB
Protein numb.
      
 0.519
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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