Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SRD5A23-oxo-5-alpha-steroid 4-dehydrogenase 2. (255 aa)    
Predicted Functional Partners:
SRD5A3
Polyprenol reductase.
     
0.954
LOC110474232
Aromatase; Belongs to the cytochrome P450 family.
     
 0.952
LOC110480744
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase.
     
 0.930
HSD17B2
Estradiol 17-beta-dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.930
AKR1D1
3-oxo-5-beta-steroid 4-dehydrogenase.
     
 0.929
CYP17A1
Steroid 17-alpha-hydroxylase/17,20 lyase; Belongs to the cytochrome P450 family.
     
 0.924
SRD5A1
3-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)).
  
  
 
0.904
LOC110471710
UDP-glucuronosyltransferase 2A2 isoform X1.
   
 
 0.903
LOC110475456
UDP-glucuronosyltransferase 1-6.
   
 
 0.903
DGAT1
Diacylglycerol O-acyltransferase 1; Belongs to the cytochrome P450 family.
   
 
  0.902
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
Server load: low (10%) [HD]