Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TGThyroglobulin. (2659 aa)    
Predicted Functional Partners:
TPO
Thyroid peroxidase.
   
 
 0.881
MB
Myoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
      
 0.839
FOXE3
Forkhead box protein E4.
     
 0.801
TSHB
Thyrotropin subunit beta.
      
 0.795
RPS13
40S ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family.
     
 0.722
TSHR
Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
      
 0.718
TRH
Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
      
 0.706
HSPA5
Glucose-regulated protein; Belongs to the heat shock protein 70 family.
    
 
 0.641
PDIA4
Protein disulfide-isomerase.
   
 
 0.608
RBP4
Retinol-binding protein 4; Belongs to the calycin superfamily. Lipocalin family.
   
  
 0.598
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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