Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC110477872Mitochondrial uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. (413 aa)    
Predicted Functional Partners:
GPAT4
Glycerol-3-phosphate acyltransferase 4.
      
 0.798
LOC110469168
Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.
      
 0.750
PPARGC1A
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha.
   
 0.733
ACADM
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial.
      
 0.728
SLC25A27
Mitochondrial uncoupling protein 4; Belongs to the mitochondrial carrier (TC 2.A.29) family.
     
  0.719
TSHB
Thyrotropin subunit beta.
   
  
 0.717
PRDX3
Thioredoxin-dependent peroxide reductase, mitochondrial.
      
 0.708
PRDM16
PR domain zinc finger protein 16.
     
 0.706
PCK1
Phosphoenolpyruvate carboxykinase, cytosolic [GTP].
   
  
 0.685
PPARG
Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]
   
 0.684
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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