| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGO1 | AGO2 | ENSLSDP00000020970 | ENSLSDP00000001663 | Protein argonaute-1; Belongs to the argonaute family. | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | 0.923 |
| AGO1 | DDX20 | ENSLSDP00000020970 | ENSLSDP00000007460 | Protein argonaute-1; Belongs to the argonaute family. | Putative ATP-dependent RNA helicase DDX20; Belongs to the DEAD box helicase family. | 0.552 |
| AGO1 | DDX6 | ENSLSDP00000020970 | ENSLSDP00000010415 | Protein argonaute-1; Belongs to the argonaute family. | Putative ATP-dependent RNA helicase DDX6. | 0.695 |
| AGO1 | DICER1 | ENSLSDP00000020970 | ENSLSDP00000010672 | Protein argonaute-1; Belongs to the argonaute family. | Endoribonuclease Dicer; Belongs to the helicase family. Dicer subfamily. | 0.886 |
| AGO1 | GEMIN4 | ENSLSDP00000020970 | ENSLSDP00000012513 | Protein argonaute-1; Belongs to the argonaute family. | Gem-associated protein 4. | 0.566 |
| AGO1 | TARBP2 | ENSLSDP00000020970 | ENSLSDP00000005055 | Protein argonaute-1; Belongs to the argonaute family. | RISC-loading complex subunit TARBP2. | 0.777 |
| AGO1 | TARBP2-2 | ENSLSDP00000020970 | ENSLSDP00000005052 | Protein argonaute-1; Belongs to the argonaute family. | RISC-loading complex subunit TARBP2. | 0.851 |
| AGO1 | TNRC6B | ENSLSDP00000020970 | ENSLSDP00000003475 | Protein argonaute-1; Belongs to the argonaute family. | Trinucleotide repeat-containing gene 6B protein. | 0.686 |
| AGO1 | TSNAX | ENSLSDP00000020970 | ENSLSDP00000023218 | Protein argonaute-1; Belongs to the argonaute family. | Translin-associated protein X. | 0.660 |
| AGO2 | AGO1 | ENSLSDP00000001663 | ENSLSDP00000020970 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Protein argonaute-1; Belongs to the argonaute family. | 0.923 |
| AGO2 | AGO3 | ENSLSDP00000001663 | ENSLSDP00000020963 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily. | 0.923 |
| AGO2 | DDX20 | ENSLSDP00000001663 | ENSLSDP00000007460 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Putative ATP-dependent RNA helicase DDX20; Belongs to the DEAD box helicase family. | 0.950 |
| AGO2 | DDX6 | ENSLSDP00000001663 | ENSLSDP00000010415 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Putative ATP-dependent RNA helicase DDX6. | 0.949 |
| AGO2 | DICER1 | ENSLSDP00000001663 | ENSLSDP00000010672 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Endoribonuclease Dicer; Belongs to the helicase family. Dicer subfamily. | 0.997 |
| AGO2 | GEMIN4 | ENSLSDP00000001663 | ENSLSDP00000012513 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Gem-associated protein 4. | 0.953 |
| AGO2 | TARBP2 | ENSLSDP00000001663 | ENSLSDP00000005055 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | RISC-loading complex subunit TARBP2. | 0.924 |
| AGO2 | TARBP2-2 | ENSLSDP00000001663 | ENSLSDP00000005052 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | RISC-loading complex subunit TARBP2. | 0.949 |
| AGO2 | TNRC6B | ENSLSDP00000001663 | ENSLSDP00000003475 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Trinucleotide repeat-containing gene 6B protein. | 0.968 |
| AGO2 | TSNAX | ENSLSDP00000001663 | ENSLSDP00000023218 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Translin-associated protein X. | 0.948 |
| AGO3 | AGO2 | ENSLSDP00000020963 | ENSLSDP00000001663 | Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily. | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | 0.923 |
