close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDKN1ACyclin-dependent kinase inhibitor 1. (151 aa)    
Predicted Functional Partners:
SKP2
S-phase kinase-associated protein 2.
    
 0.987
CCNE1
G1/S-specific cyclin-E1; Belongs to the cyclin family.
   
 0.981
CCNE2
G1/S-specific cyclin-E2; Belongs to the cyclin family.
   
 0.980
SKP1
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 0.979
CCND1
G1/S-specific cyclin-D1; Belongs to the cyclin family.
   
 0.979
CUL1
Cullin-1; Belongs to the cullin family.
    
 0.979
CCNA2
Cyclin-A2; Belongs to the cyclin family.
    
 0.979
CDK6
Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily.
   
 0.973
CCNA1
Cyclin-A1; Belongs to the cyclin family.
    
 0.973
CCND2
G1/S-specific cyclin-D2; Belongs to the cyclin family.
   
 0.968
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.