STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KMT2DHedgehog protein; Intercellular signal essential for a variety of patterning events during development; Belongs to the hedgehog family. (1013 aa)    
Predicted Functional Partners:
RBBP5
Retinoblastoma-binding protein 5.
    
 0.908
CAMKMT
Calmodulin-lysine N-methyltransferase.
     
 0.903
KMT2D-2
[histone H3]-lysine4 N-trimethyltransferase MLL2.
 
      0.900
ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2.
    
 0.898
KDM6A
Lysine-specific demethylase 6A.
   
 0.862
NCOA6
Nuclear receptor coactivator 6.
   
 0.856
WDR5
WD repeat-containing protein 5.
   
 0.789
PAXIP1
PAX-interacting protein 1.
   
 0.788
PRKAB1
5'-AMP-activated protein kinase subunit beta-1.
    
  0.777
ENSLSDP00000000734
annotation not available
    
 0.759
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.