Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DHHDesert hedgehog protein. (413 aa)    
Predicted Functional Partners:
PTCH1
Protein patched 1.
   
 0.990
DISP1
Protein dispatched 1.
   
 0.988
HHIP
Hedgehog-interacting protein.
    
 0.986
PTCH2
Protein patched 1.
   
 0.983
BOC
Brother of CDO.
    
 0.980
CDON
Cell adhesion molecule-related protein.
    
 0.980
GAS1
Growth arrest-specific protein 1.
    
 0.950
IHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
  
  
 
0.939
LRP2
Low-density lipoprotein receptor-related protein 2.
     
 0.903
SHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
  
  
 
0.901
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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