Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HDAC2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (488 aa)    
Predicted Functional Partners:
RB1
Retinoblastoma-associated protein.
   
 0.973
SIN3A
Paired amphipathic helix protein Sin3a.
   
 0.965
SMAD4_0
Mothers against decapentaplegic homolog.
   
 0.953
SNAPIN
Mothers against decapentaplegic homolog 4-like.
   
 0.953
RBPJ
Suppressor of hairless.
   
 0.950
RBPJL
Recombining binding protein suppressor of hairless-like protein.
   
 0.948
NCOR2
Nuclear receptor corepressor 2.
    
 0.938
NCOR1
Nuclear receptor corepressor 1.
    
 0.938
SKI
Ski oncogene.
    
 0.920
LOC110477357
C-terminal-binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.910
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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