STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF169E3 ubiquitin-protein ligase RNF169. (496 aa)    
Predicted Functional Partners:
USP7
Ubiquitin carboxyl-terminal hydrolase 7; Belongs to the peptidase C19 family.
    
 
 0.902
TP53BP1
Tumor suppressor p53-binding protein 1.
    
 0.805
UBE2N
Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.775
UBA52
Ubiquitin-60S ribosomal protein L40.
    
 0.706
RPS27A
Ubiquitin-40S ribosomal protein S27a.
   
  0.698
FUS1
Ubiquitin-60S ribosomal protein L40.
   
  0.698
RNF8
E3 ubiquitin-protein ligase RNF8.
     
 0.695
BRCA1
Breast cancer type 1 susceptibility.
    
 0.668
PAXIP1
PAX-interacting protein 1.
   
 0.664
XRCC6
X-ray repair cross-complementing protein 5.
     
 0.633
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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