Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NEUROD4Neurogenic differentiation factor. (319 aa)    
Predicted Functional Partners:
PAX6
Paired box protein Pax-6.
   
 0.620
TANA
Tanabin; Belongs to the intermediate filament family.
      
 0.533
LOC110484130
Transcription factor 4.
    
 
 0.528
TCF3
Transcription factor E2-alpha.
    
 
 0.528
TCF12
Transcription factor 12.
    
 
 0.528
RFX6
DNA-binding protein RFX6.
   
  
 0.488
EP300
Histone acetyltransferase p300.
    
 
 0.471
INS
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
 
 0.461
DLX2
Distal-less homeobox 2.
   
  
 0.453
TBR1
T-box brain protein 1.
   
  
 0.450
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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