FGD2 protein (Lonchura striata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

FGD2

FYVE, RhoGEF and PH domain-containing protein 2. (516 aa)

Predicted Functional Partners:

CDC42

0.610

CRIP1

0.586

SHC2

0.547

ITSN2

0.510

ITSN1

0.444

INPP5F

0.434

SH3TC2

0.409

Your Current Organism:

Lonchura striata

NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	FGD2	ENSLSDP00000021197	ENSLSDP00000001791	Cell division control protein 42.	FYVE, RhoGEF and PH domain-containing protein 2.	0.610
CDC42	ITSN1	ENSLSDP00000021197	ENSLSDP00000012112	Cell division control protein 42.	Intersectin-1.	0.984
CDC42	ITSN2	ENSLSDP00000021197	ENSLSDP00000003205	Cell division control protein 42.	Intersectin-2.	0.900
CRIP1	FGD2	ENSLSDP00000012884	ENSLSDP00000001791	Cysteine-rich protein 1.	FYVE, RhoGEF and PH domain-containing protein 2.	0.586
FGD2	CDC42	ENSLSDP00000001791	ENSLSDP00000021197	FYVE, RhoGEF and PH domain-containing protein 2.	Cell division control protein 42.	0.610
FGD2	CRIP1	ENSLSDP00000001791	ENSLSDP00000012884	FYVE, RhoGEF and PH domain-containing protein 2.	Cysteine-rich protein 1.	0.586
FGD2	INPP5F	ENSLSDP00000001791	ENSLSDP00000025533	FYVE, RhoGEF and PH domain-containing protein 2.	Phosphatidylinositide phosphatase SAC2.	0.434
FGD2	ITSN1	ENSLSDP00000001791	ENSLSDP00000012112	FYVE, RhoGEF and PH domain-containing protein 2.	Intersectin-1.	0.444
FGD2	ITSN2	ENSLSDP00000001791	ENSLSDP00000003205	FYVE, RhoGEF and PH domain-containing protein 2.	Intersectin-2.	0.510
FGD2	SH3TC2	ENSLSDP00000001791	ENSLSDP00000022301	FYVE, RhoGEF and PH domain-containing protein 2.	SH3 domain and tetratricopeptide repeat-containing protein 2.	0.409
FGD2	SHC2	ENSLSDP00000001791	ENSLSDP00000011821	FYVE, RhoGEF and PH domain-containing protein 2.	SHC-transforming protein 2.	0.547
INPP5F	FGD2	ENSLSDP00000025533	ENSLSDP00000001791	Phosphatidylinositide phosphatase SAC2.	FYVE, RhoGEF and PH domain-containing protein 2.	0.434
INPP5F	SHC2	ENSLSDP00000025533	ENSLSDP00000011821	Phosphatidylinositide phosphatase SAC2.	SHC-transforming protein 2.	0.411
ITSN1	CDC42	ENSLSDP00000012112	ENSLSDP00000021197	Intersectin-1.	Cell division control protein 42.	0.984
ITSN1	FGD2	ENSLSDP00000012112	ENSLSDP00000001791	Intersectin-1.	FYVE, RhoGEF and PH domain-containing protein 2.	0.444
ITSN1	ITSN2	ENSLSDP00000012112	ENSLSDP00000003205	Intersectin-1.	Intersectin-2.	0.797
ITSN2	CDC42	ENSLSDP00000003205	ENSLSDP00000021197	Intersectin-2.	Cell division control protein 42.	0.900
ITSN2	FGD2	ENSLSDP00000003205	ENSLSDP00000001791	Intersectin-2.	FYVE, RhoGEF and PH domain-containing protein 2.	0.510
ITSN2	ITSN1	ENSLSDP00000003205	ENSLSDP00000012112	Intersectin-2.	Intersectin-1.	0.797
SH3TC2	FGD2	ENSLSDP00000022301	ENSLSDP00000001791	SH3 domain and tetratricopeptide repeat-containing protein 2.	FYVE, RhoGEF and PH domain-containing protein 2.	0.409