STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERBB4Receptor tyrosine-protein kinase erbB-4. (424 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor-bound protein 2.
    
 0.986
HBEGF
Proheparin-binding EGF-like growth factor.
    
 0.979
NRG2
Pro-neuregulin-2, membrane-bound isoform.
    
 0.976
NRG1
Pro-neuregulin-1, membrane-bound isoform.
    
 0.976
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
    
 0.975
SHC1
SHC-transforming protein 1.
    
 0.969
SHC3
SHC-transforming protein 3.
    
 0.969
EREG
Proepiregulin.
    
 0.962
PIK3CB
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family.
    
 0.961
LOC110471843
Signal transducer and activator of transcription.
    
 0.956
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.