Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CHAF1AChromatin assembly factor 1 subunit A. (689 aa)    
Predicted Functional Partners:
CHAF1B
Chromatin assembly factor 1 subunit B.
   
 0.994
ASF1A
Histone chaperone ASF1.
   
 
 0.957
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 
 0.954
CBX3
Chromobox 3.
   
 
 0.909
RBBP7
Histone-binding protein RBBP7.
   
 
 0.828
RBBP4
Histone-binding protein RBBP4.
   
 
 0.828
SETDB1
Histone-lysine N-methyltransferase SETDB1.
    
 
 0.822
MCM2
DNA helicase; Belongs to the MCM family.
   
   0.791
MCM4
DNA helicase; Belongs to the MCM family.
   
 
 0.790
POLA1
DNA polymerase.
   
 
 0.790
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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