Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DENND2CDENN domain-containing protein 2C. (921 aa)    
Predicted Functional Partners:
C3orf67
Uncharacterized protein C3orf67 homolog isoform X2.
      
 0.804
RAB9A
Ras-related protein Rab-9A.
     
 0.699
RAB9B
Ras-related protein Rab-9B.
     
 0.699
RHOBTB3
Rho-related BTB domain-containing protein 3.
      
 0.688
AVL9
Late secretory pathway protein AVL9.
      
 0.568
SYTL1
Synaptotagmin like 1.
      
 0.544
NRROS
Negative regulator of reactive oxygen species.
      
 0.539
RAB35
Ras-related protein Rab-35.
    
 0.521
IFT27
Intraflagellar transport protein 27.
    
 0.521
LOC110471134
Rab proteins geranylgeranyltransferase component A 2.
   
 
  0.510
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
Server load: low (12%) [HD]