PDE6D protein (Lonchura striata) - STRING interaction network

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PDE6D

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide [...] (150 aa)

Predicted Functional Partners:

INPP5E

0.991

ARL2

0.985

ARL3

0.971

ARL13B

0.965

RPGR

0.946

ARL16

0.911

GMPR

0.901

GMPS

0.900

HPRT1

0.900

GUK1

0.900

Your Current Organism:

Lonchura striata

NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARL13B	ARL16	ENSLSDP00000013563	ENSLSDP00000003881	ADP-ribosylation factor-like protein 13B.	ADP-ribosylation factor-like protein 16.	0.502
ARL13B	ARL3	ENSLSDP00000013563	ENSLSDP00000006926	ADP-ribosylation factor-like protein 13B.	ADP-ribosylation factor-like protein 3; Belongs to the small GTPase superfamily. Arf family.	0.446
ARL13B	INPP5E	ENSLSDP00000013563	ENSLSDP00000004039	ADP-ribosylation factor-like protein 13B.	Inositol polyphosphate 5-phosphatase.	0.964
ARL13B	PDE6D	ENSLSDP00000013563	ENSLSDP00000001967	ADP-ribosylation factor-like protein 13B.	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide [...]	0.965
ARL16	ARL13B	ENSLSDP00000003881	ENSLSDP00000013563	ADP-ribosylation factor-like protein 16.	ADP-ribosylation factor-like protein 13B.	0.502
ARL16	PDE6D	ENSLSDP00000003881	ENSLSDP00000001967	ADP-ribosylation factor-like protein 16.	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide [...]	0.911
ARL2	ARL3	ENSLSDP00000009851	ENSLSDP00000006926	ADP-ribosylation factor-like protein 2.	ADP-ribosylation factor-like protein 3; Belongs to the small GTPase superfamily. Arf family.	0.438
ARL2	PDE6D	ENSLSDP00000009851	ENSLSDP00000001967	ADP-ribosylation factor-like protein 2.	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide [...]	0.985
ARL3	ARL13B	ENSLSDP00000006926	ENSLSDP00000013563	ADP-ribosylation factor-like protein 3; Belongs to the small GTPase superfamily. Arf family.	ADP-ribosylation factor-like protein 13B.	0.446
ARL3	ARL2	ENSLSDP00000006926	ENSLSDP00000009851	ADP-ribosylation factor-like protein 3; Belongs to the small GTPase superfamily. Arf family.	ADP-ribosylation factor-like protein 2.	0.438
ARL3	INPP5E	ENSLSDP00000006926	ENSLSDP00000004039	ADP-ribosylation factor-like protein 3; Belongs to the small GTPase superfamily. Arf family.	Inositol polyphosphate 5-phosphatase.	0.545
ARL3	PDE6D	ENSLSDP00000006926	ENSLSDP00000001967	ADP-ribosylation factor-like protein 3; Belongs to the small GTPase superfamily. Arf family.	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide [...]	0.971
ARL3	RPGR	ENSLSDP00000006926	ENSLSDP00000009257	ADP-ribosylation factor-like protein 3; Belongs to the small GTPase superfamily. Arf family.	X-linked retinitis pigmentosa GTPase regulator.	0.549
GMPR	GMPS	ENSLSDP00000014773	ENSLSDP00000001879	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	GMP synthase [glutamine-hydrolyzing].	0.992
GMPR	GUK1	ENSLSDP00000014773	ENSLSDP00000011484	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	Guanylate kinase.	0.922
GMPR	HPRT1	ENSLSDP00000014773	ENSLSDP00000007003	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.928
GMPR	PDE6D	ENSLSDP00000014773	ENSLSDP00000001967	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide [...]	0.901
GMPS	GMPR	ENSLSDP00000001879	ENSLSDP00000014773	GMP synthase [glutamine-hydrolyzing].	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	0.992
GMPS	GUK1	ENSLSDP00000001879	ENSLSDP00000011484	GMP synthase [glutamine-hydrolyzing].	Guanylate kinase.	0.985
GMPS	HPRT1	ENSLSDP00000001879	ENSLSDP00000007003	GMP synthase [glutamine-hydrolyzing].	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.934

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