Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ZUP1Zinc finger with UFM1-specific peptidase domain protein. (536 aa)    
Predicted Functional Partners:
UBA52
Ubiquitin-60S ribosomal protein L40.
    
 
 0.873
RPA1
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
    
   0.856
UBR5
E3 ubiquitin-protein ligase UBR5.
    
 
 0.855
RPA3
Replication protein A subunit.
    
   0.836
UBB
Polyubiquitin-B.
    
 
 0.790
LOC110471805
Ubiquitin.
    
 
 0.754
OTUD1
OTU domain-containing protein 1.
      
 0.720
NSA2
Ribosome biogenesis protein NSA2.
    
   0.716
USP30
Ubiquitin carboxyl-terminal hydrolase.
      
 0.699
USP1
Ubiquitin carboxyl-terminal hydrolase.
      
 0.691
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
Server load: low (26%) [HD]