Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
GOPCGolgi-associated PDZ and coiled-coil motif-containing protein. (454 aa)    
Predicted Functional Partners:
CFTR
Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
    
 0.886
RHOQ
Rho-related GTP-binding protein RhoQ.
    
 0.620
RHOJ
Rho-related GTP-binding protein RhoJ.
    
 0.620
TTC26
Tetratricopeptide repeat domain 26.
    
 0.579
ROS1
Proto-oncogene tyrosine-protein kinase ROS.
    
 0.567
PICK1
PRKCA-binding protein.
    
 0.564
RHOH
Rho-related GTP-binding protein RhoH.
    
 0.559
CEP85L
Centrosomal protein-like.
   
  
 0.465
CCDC62
Coiled-coil domain-containing protein 62.
      
 0.449
LOC110483333
Peripheral plasma membrane protein CASK-like.
    
 0.448
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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