Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SHROOM4Protein Shroom4. (127 aa)    
Predicted Functional Partners:
ENSLSDP00000003776
annotation not available
      
 0.679
PDE6C
Phosphodiesterase.
      
 0.570
UBE3A
Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
      
 0.568
PTGER4
Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family.
      
 0.565
ERCC3
TFIIH basal transcription factor complex helicase XPB subunit.
    
 0.559
ACTR8
Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily.
    
 0.551
SMPD3
Sphingomyelin phosphodiesterase 3.
      
 0.540
ACTR5
Actin-related protein 5; Belongs to the actin family.
    
 0.540
INO80C
INO80 complex subunit C.
    
 0.538
TMX4
Thioredoxin-related transmembrane protein 4.
    
 
 0.527
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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